Fortunately the people in this part of Canada are very good about being concerned for other travellers on this road. It is sometimes difficult to stop and take a photograph of something along the highway without someone stopping to ask if everything is OK.
On my trip I encountered only two vehicles on the route from Labrador City to Churchill Falls, which was the thinnest for traffic activity. There are many transport trucks using this route and if anything goes wrong that is most likely who you are going to encounter first. But the first thing on a trucker's mind is making good time and so you'll actually have to flag them down to get attention. There are many private cabins along all of these roads and there is a high likelihood of encountering fishing types and others getting away from the telephone and TV.
While the people are good, the access to services is not as good due to the vast distances between towns having hospitals, garages, airports, etc., and the lack of fully equipped service stations between towns en route. If for some reason you need a tow, it could possibly take over 200 kilometers to reach a garage. It might also take more time to get parts than what you are used to in the south.
See Also, Satellite phone link on the left.